@article {c5d8eb4dec634f8cbe0714cd8cacdc99,
	title = {Axonal and presynaptic FMRP: Localization, signal, and functional implications},
	journal = {Hearing Research},
	volume = {430},
	year = {2023},
	note = {Publisher Copyright: {\textcopyright} 2023 Elsevier B.V.},
	publisher = {Elsevier},
	abstract = {Fragile X mental retardation protein (FMRP) binds a selected set of mRNAs and proteins to guide neural circuit assembly and regulate synaptic plasticity. Loss of FMRP is responsible for Fragile X syndrome, a neuropsychiatric disorder characterized with auditory processing problems and social difficulty. FMRP actions in synaptic formation, maturation, and plasticity are site-specific among the four compartments of a synapse: presynaptic and postsynaptic neurons, astrocytes, and extracellular matrix. This review summarizes advancements in understanding FMRP localization, signals, and functional roles in axons and presynaptic terminals.},
	keywords = {Axon projection development, Axonal granules, Fragile X mental retardation protein, Neuropsychiatric disorders, Neurotransmitter release, RNA-Binding Proteins},
	issn = {0378-5955},
	doi = {10.1016/j.heares.2023.108720},
	author = {Xiaoyu Wang and Dalit Sela-Donenfeld and Yuan Wang}
}
